Anesthesia for In Utero Repair of Myelomeningocele
نویسندگان
چکیده
منابع مشابه
In utero myelomeningocele repair: baby steps and giant leaps for fetal surgery.
1016 May 2013 A FTER decades of preparing the theoretical framework of fetal surgery,1 the reality of it finally hit home in 2011 when Adzick et al. published their National Institutes of Health-supported study on outcomes after in utero surgery for myelomeningocele. Aptly named MOMS (Management of Myelomeningocele Study), the investigators terminated enrollment early after demonstrating that c...
متن کاملIn utero repair of fetal rat myelomeningocele affects neuromuscular development in the bladder
Fetal repair of myelomeningocele (MMC) has been proven to be beneficial for the central nervous system development; however, the effect of fetal MMC repair on bladder function remains controversial. The objective of the present study was to establish an early timepoint for in utero MMC repair using a rat model, and to investigate the changes in bladder development subsequent to that interventio...
متن کاملIn utero Repair of Myelomeningocele: Rationale, Initial Clinical Experience and a Randomized Controlled Prospective Clinical Trial.
Myelomeningocele (MMC), one of the most common congenital malformations, can result in severe lifelong disabilities, including paraplegia, hydrocephalus, Arnold-Chiari II malformation, incontinence, sexual dysfunction, skeletal deformations, and mental impairment. MMC was the first nonlethal anomaly to be treated by fetal surgery. Studies in animals provide compelling evidence that the primary ...
متن کاملLarge myelomeningocele repair
BACKGROUND Wound closure is accomplished in most cases of myelomeningocele (MMC) by undermining of the skin edges surrounding the defect. However, large defects cannot be closed reliably by this simple technique. Due to the technical challenge associated with large MMC, surgeons have devised different methods for repairing large defects. In this paper, we report our experience of managing large...
متن کاملDirect spinal anaesthesia for repair of myelomeningocele.
In 12 patients who were studied after therapy was stopped the incidence of sex chromatin was found to return to the normal female range. In six patients in whom the smears were studied at intervals of four days for 32 days during therapy the sex-chromatin incidence showed a rapid initial fall noticed within the first four days, and then minor fluctuations without further fall during the continu...
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ژورنال
عنوان ژورنال: Survey of Anesthesiology
سال: 2014
ISSN: 0039-6206
DOI: 10.1097/01.sa.0000441025.90638.e7